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Ausgewählte Publikationen
- Battis K, Florio JB, Mante M, Lana A, Naumann I, Gauer C, Lambrecht V, Müller SJ, Cobo I, Fixsen B, Kim HY, Masliah E, Glass CK, Schlachetzki JCM, Rissman RA, Winkler J, Hoffmann A (2022) CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy. J Neurosci 42(40):7673–7688. https://doi.org/10.1523/jneurosci.0417-22.2022
- Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JCM, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J (2016) α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy. Acta Neuropathologica. https://doi.org/10.1007/s00401-016-1572-y
- German A, Jukic J, Laner A, Arnold P, Socher E, Mennecke A, Schmidt MA, Winkler J, Abicht A, Regensburger M (2023) Novel Homozygous FA2H Variant Causing the Full Spectrum of Fatty Acid Hydroxylase-Associated Neurodegeneration (SPG35). Genes 15(1):14. https://doi.org/10.3390/genes15010014
- Güner F, Pozner T, Krach F, Prots I, Loskarn S, Schlötzer-Schrehardt U, Winkler J, Winner B, Regensburger M (2021) Axon-Specific Mitochondrial Pathology in SPG11 Alpha Motor Neurons. Front Neurosci-switz 15:680572. https://doi.org/10.3389/fnins.2021.680572
- Hoffmann A, Ettle B, Battis K, Reiprich S, Schlachetzki JCM, Masliah E, Wegner M, Kuhlmann T, Riemenschneider MJ, Winkler J (2019) Oligodendroglial α‐synucleinopathy‐driven neuroinflammation in multiple system atrophy. Brain Pathol 29(3):380–396. https://doi.org/10.1111/bpa.12678
- Ibrahim AA, Ollenschläger M, Klebe S, Schüle R, Jeschonneck N, Kellner M, Loris E, Greinwalder T, Eskofier BM, Winkler J, Gaßner H, Regensburger M (2024) Mobile digital gait analysis captures effects of botulinum toxin in hereditary spastic paraplegia. Eur J Neurol :e16367. https://doi.org/10.1111/ene.16367
- Kohl Z, Regensburger M, Aigner R, Kandasamy M, Winner B, Aigner L, Winkler J (2010) Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington’s disease. Bmc Neurosci 11(1):114. https://doi.org/10.1186/1471-2202-11-114
- Krach F, Stemick J, Boerstler T, Weiss A, Lingos I, Reischl S, Meixner H, Ploetz S, Farrell M, Hehr U, Kohl Z, Winner B, Winkler J (2022a) An alternative splicing modulator decreases mutant HTT and improves the molecular fingerprint in Huntington’s disease patient neurons. Nat Commun 13(1):6797. https://doi.org/10.1038/s41467-022-34419-x
- Krach F, Wheeler EC, Regensburger M, Boerstler T, Wend H, Vu AQ, Wang R, Reischl S, Boldt K, Batra R, Aigner S, Ravits J, Winkler J, Yeo GW, Winner B (2022b) Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis. Acta Neuropathol 144(3):413–435. https://doi.org/10.1007/s00401-022-02450-3
- Krumm L, Pozner T, Zagha N, Coras R, Arnold P, Tsaktanis T, Scherpelz K, Davis MY, Kaindl J, Stolzer I, Süß P, Khundadze M, Hübner CA, Riemenschneider MJ, Baets J, Günther C, Jayadev S, Rothhammer V, Krach F, Winkler J, Winner B, Regensburger M (2024a) Neuroinflammatory disease signatures in SPG11-related hereditary spastic paraplegia patients. Acta Neuropathol 147(1):28. https://doi.org/10.1007/s00401-023-02675-w
- Krumm L, Winkler J, Winner B, Regensburger M (2024b) Plasma Neurofilaments: Potential Biomarkers of SPG11‐Related Hereditary Spastic Paraplegia. Mov Disord 39(4):755–757. https://doi.org/10.1002/mds.29755
- Lambrecht V, Hanspach J, Hoffmann A, Seyler L, Mennecke A, Straub S, Marxreiter F, Bäuerle T, Laun FB, Winkler J (2020) Quantitative susceptibility mapping depicts severe myelin deficit and iron deposition in a transgenic model of multiple system atrophy. Experimental Neurology :113314. https://doi.org/10.1016/j.expneurol.2020.113314
- List J, Kohl Z, Winkler J, Marxreiter F, Doerfler A, Schmidt MA (2019) Ascending Axonal Degeneration of the Corticospinal Tract in Pure Hereditary Spastic Paraplegia: A Cross-Sectional DTI Study. Brain sciences 9(10). https://doi.org/10.3390/brainsci9100268
- Mészáros L, Himmler M, Schneider Y, Arnold P, Dörje F, Schubert DW, Winkler J (2023) Sobetirome rescues α-synuclein-mediated demyelination in an in vitro model of multiple system atrophy. Eur J Neurosci. https://doi.org/10.1111/ejn.16215
- Mishra HK, Prots I, Havlicek S, Kohl Z, Perez‐Branguli F, Boerstler T, Anneser L, Minakaki G, Wend H, Hampl M, Leone M, Brückner M, Klucken J, Reis A, Boyer L, Schuierer G, Behrens J, Lampert A, Engel FB, Gage FH, Winkler J, Winner B (2016) GSK3ß‐dependent dysregulation of neurodevelopment in SPG11‐patient induced pluripotent stem cell model. Ann Neurol 79(5):826–840. https://doi.org/10.1002/ana.24633
- Regensburger M, Spatz IT, Ollenschläger M, Martindale CF, Lindeburg P, Kohl Z, Eskofier B, Klucken J, Schüle R, Klebe S, Winkler J, Gaßner H (2022) Inertial Gait Sensors to Measure Mobility and Functioning in Hereditary Spastic Paraplegia. Neurology 99(10):e1079–e1089. https://doi.org/10.1212/wnl.0000000000200819
- Regensburger M, Türk M, Pagenstecher A, Schröder R, Winkler J (2017) VCP-related multisystem proteinopathy presenting as early-onset Parkinson disease. Neurology 89(7):746–748. https://doi.org/10.1212/wnl.0000000000004240
- Rizo T, Gebhardt L, Riedlberger J, Eberhardt E, Fester L, Alansary D, Winkler J, Turan S, Arnold P, Niemeyer BA, Fischer MJM, Winner B (2022) Store-operated calcium entry is reduced in spastin-linked hereditary spastic paraplegia. Brain 145(9):3131–3146. https://doi.org/10.1093/brain/awac122
- Utz KS, Kohl Z, Marterstock DC, Doerfler A, Winkler J, Schmidt M, Regensburger M (2022) Neuropsychology and MRI correlates of neurodegeneration in SPG11 hereditary spastic paraplegia. Orphanet J Rare Dis 17(1):301. https://doi.org/10.1186/s13023-022-02451-1
